The 3D printed tracheal splints are designed to be absorbed into the body,...
The 3D printed tracheal splints are designed to be absorbed into the body, allowing for expansion of the trachea and bronchus.
Source: Rob Felt, Georgia Tech

3D-printed tracheal splints used in groundbreaking pediatric surgery

Children’s Healthcare of Atlanta has performed Georgia’s first-ever procedure to place 3D-printed tracheal splints in a pediatric patient. A cross-functional team of Children’s surgeons used three custom-made splints, which biomedical engineers at the Georgia Institute of Technology helped create using an innovative and experimental 3D-printing technology, to assist the breathing of a 7-month-old patient battling life-threatening airway obstruction.

“We are so fortunate to work with a leading engineering school like Georgia Tech to find innovative, potentially life-saving treatment options for our patients,” said Donna Hyland, president and CEO, Children’s Healthcare of Atlanta. “This is a great example of how aligning Children’s clinical expertise with the missions of our research collaborators can improve patient outcomes. Research that can be translated into more effective care at the bedside is why our collaboration with Georgia Tech is so important for the future of pediatric care in Georgia.”

Experimental 3D-printed tracheal splint

Photo
3D printed tracheal splints are shown around a model of a patient’s trachea.
Source: Rob Felt, Georgia Tech

The patient who received the groundbreaking surgery is a 7-month-old boy battling both congenital heart disease and tracheo-bronchomalacia, a condition that causes severe life-threatening airway obstruction. During his six-month inpatient stay in the Pediatric Intensive Care Unit at Children’s, he experienced frequent episodes of airway collapse that could not be corrected by typical surgery protocols. The clinical team proposed surgically inserting an experimental 3D-printed tracheal splint, which is a novel device still in development, to open his airways and expand the trachea and bronchus.

Scott Hollister, Ph.D.,the director of the Center for 3D Medical Fabrication at Georgia Tech, developed the process for creating the tracheal splint using 3D printing technology at University of Michigan C.S. Mott Children’s Hospital prior to joining Georgia Tech. The Children’s procedure was the 15th time a 3D-printed tracheal splint was placed in a pediatric patient.  “The possibility of using 3D printing technology to save the life of a child is our motivation in the lab every day,” said Hollister. “We’re determined to develop innovative solutions that meet the needs of Georgia’s most complex pediatric patients.”

The splints were created using reconstructions of the patient’s airways from CT scans. Hollister and his team of biomedical engineers collaborated with the Global Center for Medical Innovation (GCMI) so that GCMI could create multiple versions of the splint, of varying sizes, to ensure the perfect fit was available for the surgical team to select and place around the patient’s airways during surgery. GCMI will also support the ongoing development and commercialization of the technology.

Groundbreaking procedure

In a complex 10-hour surgery, Children’s cross-functional team of surgeons successfully placed three 3D-printed splints around the patient’s trachea. The splints will eventually be absorbed into the body, allowing for expansion of the trachea and bronchus.

As the tracheal procedure concluded, the child was placed on a heart lung machine for surgical repair of his cardiac defect. Postoperative care took place in the Cardiac ICU and the Pediatric ICU at Children’s. “It’s the close relationships we have with our research collaborators that make this kind of groundbreaking procedure possible,” said Dr. Steve Goudy, who was part of the tracheal splint team . “A large number of additional physicians, support staff and outside collaborators worked together on this innovative procedure.”

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