Patient-specific 3D printed chest implant.
Patient-specific 3D printed chest implant.
Source: Queensland University of Technology

Pectus Excavatum: 3D printed scaffold implanted

Surgeons have implanted a patient suffering from a congenital defect with a novel, absorbable soft tissue reconstruction scaffold.

The world-first 3D printed chest reconstruction implant that has changed the life of a young medical student is the outcome of years of research by QUT Distinguished Professor Dietmar W. Hutmacher, an internationally recognised scientist who pioneered the use of patient-specific 3D printed scaffolds to repair bone and other tissue, and his team.

Pectus Excavatum (or funnel chest syndrome) is a rare malformation of the thorax characterized by a median or lateral depression of the sternum whereby the ribs and sternum grow inwards giving a concave appearance. Funnel chest occurs in 1 to 2% of the population. This is the most common congenital thoracic deformity.

Professor Hutmacher, the director of the ARC Industrial Transformation Centre in Additive Biomanufacturing in QUT’s Centre for Biomedical Technologies said the implant was made from porous, biodegradable material. "The implant was made to fit precisely over the chest deformity to allow the patient’s own blood vessels and fat tissue to grow into the implant to create a lasting normal shaped chest,” Professor Hutmacher said.

“The implant had to be flexible as the chest is in constant movement and so it had to have the ability to change shape without breaking. The soft tissue scaffold contained no ceramic additives that we use for rigid bone scaffolds. Our research with Dr Matthew Cheng over the past five years has shown that an implant injected with the patient’s own fat at the time of implantation would give the best chance of success.”

The surgery at Princess Alexandra was performed by Dr Michael Wagels who has collaborated closely with Professor Hutmacher for many years. “An important part of the surgery was injecting the scaffold with the patient’s own fat at the time of implant insertion to commence the reconstruction/regeneration of the highly porous scaffold with more than 90 per cent of her own tissue,” Dr Wagels said.

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