CRISPR

Device diagnoses Covid-19 from saliva samples

Engineers have designed a device that can detect SARS-CoV-2 from a saliva sample in about an hour. They showed that the diagnostic is just as accurate as the PCR tests now used.

Microfluidics: efficiently smuggling drugs into cells

Progressive Mechanoporation makes it possible to mechanically disrupt the membranes of cells for a short time period and let drugs or genes inside cells.

CRISPRoff offers unrivaled control of epigenetic inheritance

Scientists have figured out how to modify CRISPR’s basic architecture to extend its reach beyond the genome and into what’s known as the epigenome.

Designing better antibody drugs with machine learning

Artificial intelligence could help to optimise the development of antibody drugs. This leads to active substances with improved properties, also with regard to tolerability in the body.

Genome-editing tool TALEN outperforms CRISPR-Cas9

Experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome that are densely packed.

CRISPR to cure sickle cell disease

University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients’ blood cells.

COVID-19 testing: Robotic platform helps to scale up capacity

Researchers havee repurposed robotic technology normally used for synthetic biology research to help with testing for COVID-19.

Using CRISPR to knock down gene messages

Researchers have harnessed CRISPR technology to target gene messages (messenger RNA) involved in early vertebrate

Harnessing the power of CRISPR in space and time

Researchers have developed the revolutionary “CRISPR-Switch”, which enables unprecedented control of the CRISPR technique in both space and time.

Using CRISPR to detect diseases

Researchers present sensor prototype that can rapidly, precisely, and cost-effectively measure molecular signals for cancer.

Revolutionising CRISPR-Cas

Researchers have refined the famous CRISPR-Cas method. Now, for the very first time, it is possible to modify dozens, if not hundreds, of genes in a cell simultaneously.

CRISPR-powered device detects genetic mutations in minutes

Engineers have combined CRISPR with electronic transistors made from graphene to create a new hand-held device that can detect specific genetic mutations in a matter of minutes.

CasX, the smaller CRISPR gene editor

Scientists find new and smaller gene editor: the new gene-editing protein, CasX, may give CRISPR-Cas9 a run for its money.

CRISPR/Cas9 shown to limit impact of parasitic diseases

Researchers successfully used CRISPR/Cas9 to limit the impact of schistosomiasis and liver fluke infection, affecting more than a quarter of a billion people in Southeast Asia, sub-Saharan Africa, and Latin America.

CRISPR repurposed to develop better antibiotics

Researchers have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

CRISPR: Giving Cas9 an ‘on’ switch

Researchers have given CRISPR-Cas9 an “on” switch, allowing users to keep the #Cas9 gene editor turned off in all cells except its designated target.

CRISPR opens door to new therapy options- ‘genome surgery’

Scientists plan to edit their genomes to correct rare genetic mutations and slow or halt progression of their diseases.

Liver-on-a-chip, the ideal test environment for CRISPR

Research project is aimed at improving therapeutic options for both rare and common diseases, including supporting methods to improve editing the human genome.