CRISPR

Device diagnoses Covid-19 from saliva samples

Device diagnoses Covid-19 from saliva samples

Engineers have designed a device that can detect SARS-CoV-2 from a saliva sample in about an hour. They showed that the diagnostic is just as accurate as the PCR tests now used.

Microfluidics: efficiently smuggling drugs into cells

Microfluidics: efficiently smuggling drugs into cells

Progressive Mechanoporation makes it possible to mechanically disrupt the membranes of cells for a short time period and let drugs or genes inside cells.

CRISPRoff offers unrivaled control of epigenetic inheritance

CRISPRoff offers unrivaled control of epigenetic inheritance

Scientists have figured out how to modify CRISPR’s basic architecture to extend its reach beyond the genome and into what’s known as the epigenome.

Designing better antibody drugs with machine learning

Designing better antibody drugs with machine learning

Artificial intelligence could help to optimise the development of antibody drugs. This leads to active substances with improved properties, also with regard to tolerability in the body.

Genome-editing tool TALEN outperforms CRISPR-Cas9

Genome-editing tool TALEN outperforms CRISPR-Cas9

Experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome that are densely packed.

CRISPR to cure sickle cell disease

CRISPR to cure sickle cell disease

University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients’ blood cells.

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