genetics

CRISPRoff offers unrivaled control of epigenetic inheritance

CRISPRoff offers unrivaled control of epigenetic inheritance

Scientists have figured out how to modify CRISPR’s basic architecture to extend its reach beyond the genome and into what’s known as the epigenome.

Explainable AI for decoding genome biology

Explainable AI for decoding genome biology

Researchers have developed advanced explainable AI in a technical tour de force to decipher regulatory instructions encoded in DNA.

How genetic motifs conduct "the music of life"

How genetic motifs conduct "the music of life"

​Using AI and supercomputers, researchers have discovered reoccurring patterns and combinations of the four molecular building blocks A, C, G and T.

Genome-editing tool TALEN outperforms CRISPR-Cas9

Genome-editing tool TALEN outperforms CRISPR-Cas9

Experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome that are densely packed.

CRISPR to cure sickle cell disease

CRISPR to cure sickle cell disease

University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients’ blood cells.

Precision health in the palm of your hand

Precision health in the palm of your hand

Recent breakthrough developments in technologies for real-time genome sequencing, analysis, and diagnosis are poised to deliver a new standard of personalized care.

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